Best thing to do is start simple. Check all the wheel nuts are nice and tight, then jack each corner up one at a time and try to wobble the wheel to check the bearings. If they're fine, then it's time to go and get the wheel balance checked. It's best to have them perfectly balanced, as it saves you tyres! As the wheel spins, if it's out of balance, the vibrations go through the tyres, and can put little bumps on the tread, which isn't good at all. When I worked at Just Tyres, we used to sometimes check the balance for free if we were bored/quiet, most of the customers just gave us £10 for it anyway, which was nice.