Yep, I've done it on my last 3 front mod wheels, never had a problem. As Mark said, the Silver Sky bikes came with 2x rear wheel and again no issues.
Mike - Which spoke calcs are you using? Which dimensions for hub and rim? I'm 99% confident the spoke sheet with your order is correct, 175 disc 2x and 177 non disc 2x will build up perfectly. I probably built 1 of these wheels per week a couple of years ago. Your notes didn't specify a lacing pattern so in these cases we go with something that's a good balance of weight, strength and uses the closest lengths to what we have in stock - for example, if 3x is 188 and we only have 186, we'll check what lengths are needed for 2x and if it's closer we'll go with that. If you do want to send them back for refund or exchange though then no problem at all, our returns form is in the T&Cs section of the site.
Forteh - Emailing/calling people to ask about lacing patterns is usually fruitless and a waste of everyone's time - it's rare for customers to know what they want (and if they do, they'll put it in the notes) and it often adds another 24-48 hours onto the overall ordering process, which nobody wants!