Can only speak from my own experiences but 100vg tends to wick slower (more regular dry hits) gunks up the coils quicker (again, more regular dry hits) and has less flavour. I prefer 80/20. But 100 is certainly not dumb, I do drip it from time to time in the right flavours *oh, one of the guys at grey haze was so impressed with the billow fused Clapton he's asked me to coil his. Haha, I'm coiling for the pro's